Lodz University of Technology presents potential sterilization methods for Optogenerapy bio-electronic implant
Optogenerapy partner Lodz University of Technology has attended at the Annual Conference of Biomaterials in Medicine and Veterinary Medicine, which has taken place in Rytro, Poland, on 2018 October 11-14. During the Conference, members of the Institute of Applied Radiation Chemistry from theLodz University of Technology have presented the poster “Potential Sterilization Methods for Implantable Device for Therapeutic Delivery”, a thorough review of potential methods for the sterilization of Optogenerapy’s bio-electronic implant.
After analysing several sterilization methods, from thermal, low-temperature to aseptic processing procedures, researchers from the Lodz University of Technology have concluded that an over-room temperature (up to 40-60º) sterilization using Ethylene Oxide, H2O2low-temperature plasma or low-temperature steam & formaldehyde are the most suitable ones for the implant.
Optogenerapyproposes a new optogenetics implant for controlled beta interferon (IFN-ß) protein delivery for treating patients suffering from Multiple Sclerosis. The device, to be implanted subcutaneously, includes a cell chamber and an optoelectronics module controlling the generation of the IFN- ß drugand it needs to be provided completely sterile.
Having selected the sterilisation methods, now these procedures will be validated experimentally in order to assure that the physical and chemical properties of the implant are not altered and it remains biocompatible.
The Annual Conference of Biomaterials in Medicine and Veterinary Medicine addresses both fundamental and clinical applications of carbon, metals, polymers, ceramics and composite biomaterials. The aim of the Conference is to present the latest results of scientific research as well as to exchange ideas, knowledge and experience of scientists, researchers and clinicians in the field of biomaterials.